Chsy1 Polyclonal Antibody

Basic Info.

Model NO.	BS62336
Specification	100ug/1mg
Trademark	Bioworld
Origin	China
Production Capacity	3000 Vials

Product Description

Catalog No.	BS62336
Product Name	CHSY1 polyclonal antibody
Applications	WB IHC
Alternative Name	Chondroitin sulfate synthase 1; Chondroitin glucuronyltransferase 1; Chondroitin synthase 1; ChSy-1; Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase 1; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1; N-acetylgalactosaminyltransferase 1; CHSY1; CHSY; CSS1; KIAA0990; UNQ756; PRO1487
Swiss-Prot	Q86X52
Host	Rabbit
Reactivity	Human,Mouse,Rat
Application_all	WB: 1:500~1:1000 IHC: 1:50~1:200
Product	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity	CHSY1 polyclonal antibody detects endogenous levels of CHSY1 protein.
BiowMW	~ 91 kDa
Note	For research use only, not for use in diagnostic procedure.
Immunogen	Synthetic peptide, corresponding to Human CHSY1.

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  Western blot (WB) analysis of CHSY1 polyclonal antibody at 1:500 dilution LaneA:HEK293T whole cell lysate LaneB:PC12 whole cell lysate LaneC:AML-12 whole cell lysate

Background

Chondroitin sulfate synthase 1, has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Involved in the negative control of osteogenesis likely through the modulation of NOTCH signaling.