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Roche has paid US$310 million upfront, and committed up to $2.5 billion in milestones, to partner with Alnylam on the development and commercialization of zilebesiran, an angiotensinogen-targeted RNAi drug. Zilebesiran is in two ongoing phase II trials for hypertension that are due to read out in 2023 and 2024.
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doi: https://doi.org/10.1038/d41573-023-00131-8
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